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In this study, ApoE / mice were treated with GLP-1(736)amide, GLP-1(936)amide, GIP(142) or GIP(342) injections for the course of 4 weeks

These findings highlight a bidirectional relationship: GLP-1 RAs can modulate the gut microbiota, while the pre-existing microbial configuration may influence therapeutic efficacy and reflect the degree of dysbiosis in T2D ( More recent real-world analyses on gut microbiome fecal samples of patients with T2D

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