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For example, if phenytoin levels are therapeutic, the administration of a drug competing for protein binding could double the free phenytoin level (if protein binding decreases from 90% to 80%)
As important as understanding what is in your skinny shot is knowing who is giving it to you
C.JasonL
When this happens it's binding becomes irreversible ( aging ) and the complex becomes resistant to the effects of oxime regenerators such as pralidoxime Aging develops within 3-5 hours with sarin
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