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Retatrutide has progressed into Phase 3 programs targeting obesity (with and without diabetes), focusing on durability of weight loss, cardiometabolic outcomes, and broader population validation

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Therapeutic benefits to the cardiovascular and renal systems are emerging yet it currently remains unresolved if these are via direct actions on GLP-1R on these tissues or an indirect effect mediated by the health benefits of weight loss

Researchers dont yet understand exactly how GLP-1 drugs work for AUD, according to Dr