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Starting low and escalating gradually produced fewer gastrointestinal side effects than starting directly at a higher dose, which is why the 2mg +2mg-every-4-weeks schedule became the standard escalation approach in the published data
The longevity-curious early adopter is the most interesting case
Maintaining motivation during slow progress can be challenging
Most health insurance plans sort medications into three to five tiers, with higher tiers carrying higher out-of-pocket costs to the patient
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