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Site rotation and reconstitution/storage review are standard clinical guidance
Structurally identical to the biologically active 129 N-terminal amino acids of native GHRH, Sermorelin preserves full receptor agonist activity
However, the affinity towards the diphenolic substrate L -DOPA, which features a carboxyl group, increased ( K m = 4.2 mM) in contrast to dopamine, which showed a decreased affinity ( K m = 2.36 mM, Table 2)
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