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Mitophagy as a central component of cardiac mitochondrial quality control Parallel to macroautophagy, mitophagy plays a particularly critical role in safeguarding mitochondrial quality control (MQC), especially given the extreme energetic demands of the heart

Parekkadan B, Milwid JM

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Combination regimens with CQ/HCQ improve outcomes when paired with radiation therapy in brain metastases, 284,285 HDAC inhibitors such as vorinostat, 286 mTOR inhibitors such as temsirolimus, 287 temozolomide, 288 proteasome inhibitors such as bortezomib, 289 gemcitabine in pancreatic ductal adenocarcinoma, 290 and erlotinib in non-small cell lung cancer (Fig

Fine lines respond best