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Reduced levels of SLC7A11 have been observed in fibroblasts associated with IPF, which exhibit a senescent phenotype [209]
Journal of Psychiatric Practice, 16(1), 514
Several 20242025 integrative meta-analyses also show that adding microbial metabolites (SCFAs, bile acids, LPS/LBP) and systemic inflammatory markers to microbiome-based models significantly improves diagnostic accuracy, implying that microbiome changes are informative but insufficient for high-fidelity prediction [190]
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