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Since founding Noctrix, our mission has been to deliver innovative, non-pharmacologic solutions for people living with RLS who have limited treatment options, says Shri Raghunathan, president and CEO of Noctrix Health, in a release
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One of the first major innovations and breakthroughs was the gelatin-coating of pills and capsules, which made them easier to swallow
Further examination demonstrated that responders to pioglitazone had increased plasma concentrations of pioglitazone83 and genetic analysis identified a variant of CYP2C8 (the gene that encodes the predominant pioglitazone-metabolizing enzyme) that was associated with fibrosis score84
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