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Effects of L-Carnitine on Mineral metabolism in the Multicentre, Randomized, double blind, placebo-controlled CARNIDIAL Trial

Citrate entering the cytoplasm can indirectly inhibit glycolysis by acting on pyruvate kinase (PK), stimulate fatty acid synthesis by activating acetyl-CoA carboxylase (ACC), and promote gluconeogenesis by activating fructose-1,6-bisphosphatase (111)