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Overall, the study demonstrated that AOD9604 affects metabolic parameters in both lean and obese mice, as well as in genetically modified mouse models lacking 3-adrenergic receptors

However, for anyone with absorption issues (like pernicious anemia or IBD), oral supplements are often insufficient

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Also relevant, even when administered at concentrations considerably greater than ours (e.g., 1000 mg/Kg), APAP-induced hepatotoxicity in rodents can result in no changes to plasma ammonia levels or prothrombin time 83

[2] Sercombe, L., et al