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Reducing carbohydrate intake, increasing protein, cycling caloric intake, or implementing time-restricted eating windows can break through metabolic adaptation
Referral to specialist weight management services for intensive behavioural interventions, very-low-calorie diets, or consideration for bariatric surgery Bariatric surgery remains the most effective intervention for significant, sustained weight loss
The future looks brighter than ever for patients, and the science driving it
MI serves as a key mediator of insulin signaling by generating inositolphosphoglycan (IPG) second messengers, which facilitate glucose uptake, glycogen synthesis, and lipid oxidation (135)
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