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doi:10.1056/nejmoa2307563 14.Vambe S, Zulu W, Hough E, Luvhimbi M, Rwizi S, Bronkhorst E
Their highly conserved regulatory, kinase, and association domains make isoform selectivity a key challenge, as each has distinct tissue-specific functions, and off-target inhibition may cause toxicity
Here, we will explore the specific considerations for patients with hypothyroidism, hyperthyroidism, thyroid nodules, goiters, and thyroid cancer
A microdosing tirzepatide chart can help structure this approach
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