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Expert Opin Pharmacother 12:16231632 Benkert O, Muller M, Szegedi A (2002) An overview of the clinical efficacy of mirtazapine
Further research on biomarkers is a promising direction for the development of new therapeutic strategies
7 Summary and outlook SSRIs are the most widely used antidepressant drugs in the world
Among the enzymes related to GSH metabolism, glutathione S-transferases (GSTs, EC 2.5.1.18) catalyze the binding of various xenobiotics (including numerous pesticides) and their electrophilic metabolites with GSH to produce less toxic and more water-soluble conjugates, so this isoenzyme family has a distinct role in plant detoxification reactions (Marrs 1996, Edwards et al
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