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Because long-term disability often reflects network disconnection, metabolism-focused studies should assess myelin integrity, axonal conduction, diffusion-tensor imaging, and preservation of the corpus callosum and corticospinal tracts

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Three RCTs [13, 33, 34] involving 186 patients provided low certainty evidence (Table 2) that L-carnitine supplementation may induce or no difference in changes in the total cholesterol levels (MD: 11.80, 95%CI: 27.13 to 3.53)