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It explains why two patients taking similar medications may have entirely different treatment journeys, and why the expansion of GLP-1 use has created both opportunities and tensions within healthcare systems

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Under physiological conditions plasma glutamate concentration, 10-20uM, is limiting for GDH flux supplying TCA intermediates while plasma glutamine concentration, 600uM, is not [2]

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You may need a different treatment Ozempic gets a lot of attention, but its not the only option for weight loss and its not even FDA-approved specifically for that use