Once injectable semaglutide was approved for weight loss in 2021 (under the trademark of Wegovy), TV advertising took off, and the world never looked back
The test examines key variants including GIPR rs1800437, FTO rs9939609, and MC4R rs17782313each influencing appetite regulation, metabolic rate, and medication responsiveness
Therefore, in patients where the fasting glucose is a more dominant feature of their hyperglycemia, metformin may be more appropriate, while GLP-1RAs could be better suited for those with postprandial hyperglycemia
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Safety and tolerability were predefined as the primary endpoint and assessed by treatment-emergent adverse events (TEAEs)
