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Some individuals carry genetic variations that reduce conversion efficiency
There are also other manifestations of pemphigus, induced by IgG against multiple cytoplasmic plakin proteins, and even variants of pemphigus mediated by IgA Abs
Therefore, reducing the dose or discontinuing the supplement may alleviate these symptoms
While these anecdotes can be compelling, they dont account for natural recovery, placebo effects, or individual variationwhich is why they sit firmly at the bottom of the evidence hierarchy
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