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and Supporting muscle and nerve function
Hyperglucagonemia increases resting metabolic rate in man during insulin deficiency
Stimulates metabolism and appetite
The activation of GPER in MC3T3-E1 osteoprogenitor cells significantly upregulates the expression of mineralization-related markers, including alkaline phosphatase, osteocalcin, and type I collagen, underscoring its positive contribution to bone formation [110]
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