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Combined deficiency in glutathione peroxidase 4 and vitamin E causes multiorgan thrombus formation and early death in mice

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Additionally, a combination therapy involving glucose, niacin, and N-acetylcysteine has been shown to synergistically improve respiratory chain complex I dysfunction, reduce mitochondrial stress, and boost metabolic and glutathione levels, thereby increasing resilience and preventing acute neurological and biochemical decompensation