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Crucially, this happens without IGF-1 stimulation
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Key Differences Between AOD 9604 and MOTS-C | Feature | AOD 9604 | MOTS-C | |-----------------------|-------------------------------------|----------------------------------------| | Origin | HGH fragment | Mitochondrial peptide | | Primary function | Fat metabolism and fat loss | Cellular energy regulation and metabolism | | Effects on hormones | Minimal impact on HGH and insulin | Improves insulin sensitivity | | Common goals | Weight loss, fat reduction | Energy boost, metabolic health | | Research status | Several clinical trials on fat loss | Emerging research on metabolism | These differences mean the peptides serve different purposes, even though both relate to metabolism
Because the fragment lacks the regions responsible for the somatogenic activity of the parent hormone, published models report no accompanying insulin-like growth factor 1 elevation, which is the functional separation that defines its research value
Adequate levels support normal energy metabolism, which may help reduce fatigue related to deficiency
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