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Danger JM, Tonon MC, Jenks BG, Saint-Pierre S, Martel JC, Fasolo A, et al
Presented for research literature review only Wurtman RJ et al
PAC-1 receptors do not have ligand binding activity until platelet activation and then contributes to platelet thrombus formation
This unique iron dependency renders tumor cells to become susceptible to iron overload, making it possible to develop ferroptosis-mediated therapy
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