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For weight management specifically, the FDA has approved semaglutide 2.4 mg weekly (Wegovy), liraglutide 3.0 mg daily (Saxenda), and tirzepatide (Zepbound) for adults with BMI 30 kg/m or 27 kg/m with at least one weight-related comorbidity
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Erivedge (vismodegib): Used for basal cell skin cancer, requires a 2-year deferral
However, the effectiveness of oral semaglutide depends on closely following the dosing instructions
No thyroid C-cell tumors were observed in human trial participants, though this risk carries a theoretical basis from rodent studies and is listed as a precaution, as it is with all GLP-1 class compounds
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