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Due to the extra steps the oral pill has to take to survive the stomach, researchers were initially concerned it might not be as effective as a direct injection
The mechanics are straightforward
Its metabolism depends on hepatic binding proteins that selectively retain alpha-tocopherol from food for its incorporation into very low-density lipoproteins and its subsequent tissue distribution, together with esterified cholesterol and triglycerides 31
Zepbound is primarily approved for weight management, but its active ingredient is also used in diabetes treatment
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