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[38] Pharmacology [edit] Tirzepatide is an analog of gastric inhibitory polypeptide (GIP), a human hormone that stimulates the release of insulin from the pancreas
Butyrate improves insulin sensitivity and increases energy expenditure in mice
The early dosing considerations for similar peptides apply to retatrutide as well
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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