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Manufacturing peptides at pharmaceutical scale is technically challenging
Significantly so
3.3 Radioactive iodine therapy The use of radioactive iodine (131I) rituximab therapy for GD is often characterized by a rapid onset of hypothyroidism, due to the destruction of the thyroid tissue caused by the radiation emitted by the 131I, which is selectively absorbed by the cells expressing the sodium-iodide symporter
DOI 10.2337/dc22-1148 - adjusted HR 1.58 (1.27-1.95) at 1-3 years
But semaglutide is expensive, costing approximately $1,000 to $1,350 per month without insurance, and no lower-cost generics are currently available
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