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Track in week 2 Which day after dose feels strongest Whether nausea, fatigue, constipation, or appetite changes repeat Meal size and foods that feel better or worse Fiber intake (begin adding bell peppers, cucumbers, kiwi, banana) Water intake stay aware, since thirst may be reduced Bowel pattern (constipation usually shows up here if it is going to) Energy and sleep Weight trend, not just today's number Week two is when the first pattern shows up

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Patients with pre-existing gastroparesis, significant gastrointestinal disease, or previous gastric surgery require particularly careful monitoring and may benefit from gastroenterology consultation before initiating GLP-1 agonist therapy

In animal models and in the clinical setting, distinct pharmaceuticals have been described to modulate the function of transporters or enzymes involved in the metabolic dynamics of amino acids (Table 11)

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