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Second , both medications can influence metabolic parameterstirzepatide through direct glucose regulation and weight loss, sermorelin through growth hormone-mediated effects on insulin sensitivity and body composition

However, Tirzepatide has gained notoriety as one of the most effective weight loss drugs currently available

The average user is estimated to gain less than 2% body weight in the first year after stopping a GLP-1

Endocrinology 154: 4-8, 2013