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Holst, who discovered and described GLP-1, explains its role as a gut-derived hormone that regulates appetite, insulin secretion, and digestion, offering a groundbreaking approach to managing obesity and type 2 diabetes
It remains in Phase 3 clinical trials under Eli Lilly's TRIUMPH program
If there is one candidate that fits that bill to explain my description, it would be inhibition of AMPK, the master regulator of metabolism (2)
All data from those monkeys were excluded from the averages unless otherwise noted