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If you are using GLP-1 medications, consult your prescribing physician about adopting a gradual weight loss strategy to give your body and skin time to adjust safely

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Schubert M, Contreras C, Franz N, Hellhammer J

The mechanism involves glycine exerting a hyperpolarizing effect on macrophages and other immune cells, inhibiting calcium influx through voltage-sensitive channels and thereby dampening their inflammatory activity

Early research suggests that Akkermansia muciniphila and Clostridium butyricum may influence pathways connected to GLP-1 signaling, but more research is needed