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For example, considering HepG2, Huh7, and Hep3B, even though they are all epithelial liver cancer cells with high expression of HNF4, HepG2 cells have normal expression of wild-type p53, Huh7 cells overexpress a mutant p53, while Hep3B cells are p53 null 65
While some people experience rapid weight loss initially, it's important to remember that this is a long-term treatment
Grimelius L, Capella C, Buffa R, Polak JM, Pearse AG, and Solcia E
Nat Rev Cancer , 2023, 23: 295316 Ruffell B, Chang-Strachan D, Chan V, Rosenbusch A, Ho CMT, Pryer N, Daniel D, Hwang ES, Rugo HS, Coussens LM
Diabetes 65 , 742754 (2016)
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