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Tumor-extrinsic factors and the microenvironmental landscape In addition to cell-autonomous mechanisms, tumor-extrinsic factors profoundly shape therapeutic outcomes

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1.14 Levothyroxine and pharmacokinetics Levothyroxine (T4) is an artificial form of thyroxine, the bodys natural thyroid hormone, and has been the mainstay of hypothyroidism treatment since the 1980s