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Weight loss usually includes both fat loss and some loss of lean muscle

Before escalating dose, review: Injection technique Adherence Caloric intake (liquid calories, grazing, alcohol) Resistance training and lean mass preservation If the patient is metabolically improving and clinically stable, dose escalation is optional

Are There Alternative Weight Loss Medications Similar to Semaglutide Tirzepatide (brand names Mounjaro and Zepbound) is the closest alternative to semaglutide and works on both GLP-1 and GIP receptors, producing slightly greater average weight loss in head-to-head data

The medication helps improve insulin sensitivity and fat oxidation, making it easier to shed excess weight

Even patients who weren't at goal on another GLP-1 agonist have seen additional weight loss and blood sugar control when switching to tirzepatide