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For example, NOX-mediated ROS formation in the kidney has been associated with zinc deficiency (Li et al

Doing so can raise compliance concerns and increase audit risk

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Furthermore, studies have shown that following the consumption of ellagitannin-rich pomegranate extract, high concentrations of UA are detected in the prostate, gut, and colon of prostate cancer model mice, whereas elevated levels of UA-sulfate and UA-glucuronide are detected in the liver and kidneys (29)

Another possibility is that obesity could lower serum vitamin B12 levels through decreased dietary intake or absorption, increased catabolism, and sequestration in adipose tissue, or changes in the gut microbiota profiles which could affect the metabolism of vitamin B12