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This is probably due to a boost in nitric oxide (NO) production, which improves blood flow and oxygen consumption in the muscles
Common Side Effects Most patients experience some side effects when starting GLP-1 medications, typically including: Nausea Reported by 20-40% of patients, usually improves over time
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Food and Drug Administration approved Foundayo (orforglipron) for adults with obesity, or for adults who are overweight and have at least one weight-related medical condition such as high blood pressure, type 2 diabetes, or high cholesterol
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