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The key is working with the appetite suppression rather than against it
By age 50 the levels of NAD+ are approximately 1/2 of those of a young adult
If prescription GLP-1 is not accessible, oral supplements with actual clinical data (berberine capsules, fiber supplementation) at least have documented effects, which is more than any patch can claim
Int J Dev Neurosci 31:2124 Ribas GS, Manfredini V, de Mari JF, Wayhs CY, Vanzin CS, Biancini GB, Sitta A, Deon M, Wajner M, Vargas CR (2010) Reduction of lipid and protein damage in patients with disorders of propionate metabolism under treatment: a possible protective role of l-carnitine supplementation
Slower gastric emptying can make bolus timing harder, especially off AID systems
