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According to MedPage Today, 10-15% of patients do not respond adequately to semaglutide, though for many others, the issue isn't non-response but diminished response over time
Wegovy, which comes in single-dose pens, has different guidelines - when refrigeration is not possible, Wegovy may be kept at temperatures up to 86F (30C) for up to 28 days
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The drug is given as a two-week course and may need to be repeated
Instead, they create exposure patterns not studied in major clinical trials, which means safety data becomes unclear
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