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Akira Harashima from Hayashibara Biochemical Lab, Fujisaki, Japan
Genetic engineering was successfully used to increase folate production by Lactococcus lactis and to transform a folate consumer, Lactobacillus gasseri , into a folate producer 867,868,869,870,871,872
FOXO4-DRI: Senolytic Peptide Mechanism and the p53-FOXO4 Axis FOXO4-DRI is a D-retro-inverso peptide that selectively kills senescent cells by disrupting the protective FOXO4-p53 interaction
This is the basis for oral and capsule research formats, especially in gut-focused models
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