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This pattern suggests that the TRICARE coverage gap is not preventing access to tirzepatide for motivated patients, but it does create a two-tier system: those with diabetes access subsidized brand-name medication, while those with obesity alone pay full cash price for compounded alternatives
Contraindications and Precautions GLP-1 agonists are contraindicated in individuals with hypersensitivity to these medications and those who are pregnant (48)
RoB 2 assesses five domains to determine the risk of bias in randomized controlled trials: the randomization process, deviations from intended interventions, missing outcome data, measurement of the outcome, and selection of the reported result
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