GLP-1 receptor agonists reduce all-cause mortality and major adverse cardiovascular events (MACE) by approximately 1213% in high-risk populations, as detailed in this 2025 review of cardiovascular effects of GLP-1 receptor agonists on PubMed
Front Pharmacol 2022;13:827896.ArticlePubMedPMC 10
Polyethylene glycol is commonly supported for constipation, while stimulant laxatives are generally used as short-term or rescue options
Research Frontier New & Potential Future Treatments The relationship between GLP-1 medications and hair is an active area of dermatologic research, and the picture is more nuanced than "GLP-1 causes hair loss." Interestingly, several case reports have also described hair regrowth or stabilization in patients on GLP-1 therapy, particularly when hair loss was originally driven by insulin resistance or metabolic dysfunction, since improved glycemic control can, in some patients, benefit certain hair loss subtypes such as central centrifugal cicatricial alopecia (CCCA) and androgenetic alopecia
3 In one experiment, the effect was reproduced even when autoantibodies were drawn from patients two years after their initial infection, suggesting the immune dysregulation can persist long after acute illness