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There are no reported risks associated with large doses of B12, since the vitamin is water soluble and excess amounts are flushed out of the system
The metformin research suggests plausibility for similar effects with semaglutide , but the mechanisms differ enough that direct extrapolation remains uncertain
Technique : The needle is inserted at a 45-degree angle to the skin
However, researchers do not know if the effects of obesity can cause a reduction in B12 levels or if reduced B12 levels may be a contributing factor to obesity
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