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The gut bacterial community plays a significant role in maintaining human wellbeing by producing many fundamental health-benefiting substances, including synthesizing vitamin K (34), promoting angiogenesis, involving host metabolic processes, and altering the appetite signaling pathway (3538)
10.3945/ajcn.114.101659 3 BarrettC
Beyond the demonstration that pharmacologic blockade of IGF-1R signaling can favorably impact lifespan, these data also provide new insights into temporal and metabolic aspects regarding this pathway and aging
But its likely due to compounds in coffee called polyphenols, not the caffeine specifically
Blood pressure changes receive mixed reports
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