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The SURPASS-SEMA trial (NCT05583292) compared tirzepatide directly to semaglutide 1.0 mg in type 2 diabetes, showing tirzepatide 10 mg and 15 mg produced superior HbA1c and weight reductions [11]

Coffee intake can also influence food intake, eating habits, and appetite regulation, which are important factors for those trying to support weight management or lose weight

JAMA 307(24):26272634

Losing muscle while losing fat means the metabolism slows more than it should, making weight maintenance harder after the medication is discontinued

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