DPP4 deficiency in rats A major part of the literature is dealing rather with DPP4-KO in rats than in mice
Information extracted from eligible articles that were tracked by the reviewers included data such as article title, authors, journal name, year of publication, article type, data source, clinical setting, patient demographics, prior patient pulmonary or gastric history, patient medications noted, system-based comorbidities, extent of adverse event, diagnostics used, study methods, study of patient outcomes, limitations, and conclusions
The results of animal experiments indicated that elevated serum TNF expression in DPN rats and elevated sciatic nerve IL-6 and IL-1 levels in diabetic rats were associated with neuropathy, this suggests that inflammatory factors may play a role in the pathogenesis of neuropathy (94, 95)
It can fit into a diabetes management plan
Journal of geriatric cardiology: JGC