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Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores

The cells were resuspended in the desired growth media to an initial optical density (OD 600 ) of 0.1

The two-hour window is a conservative, low-risk approach adopted from the broader drug-interaction guidance in the dulaglutide prescribing information

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Using the standard pharmacokinetic principle of 5 half-lives for complete elimination, and with tirzepatide's half-life of approximately 5 days, the medication reaches negligible levels around 25 days