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Weight loss depends on: Starting body weight Medication dose Diet Physical activity Sleep Consistency Average weight loss reported in clinical studies: Some individuals lose even more weight when lifestyle modifications are maintained

Tirzepatide (Mounjaro, Zepbound) is a dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist, though these medications are often collectively referred to as incretin-based therapies

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Dan Z, Lin K, Ding XF, Suo LQZ, Liu SH, Ge SLB, et al