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Bacterial deconjugation of bile acids impairs enterohepatic recirculation, reducing reabsorption efficiency and consequently disrupting lipid digestion

However, challenges remain, including fully defining ferroptosis regulation and addressing potential off-target effects of inducers

109,153 Accordingly, exposure of SW480 colorectal cancer cells to hypoxia resulted in an enrichment in mitochondria of SQR protein levels and H 2 S detoxification activity

Rotate injection sites (abdomen, thighs, upper arms) systematically to reduce local irritation and lipohypertrophy [13]

This complexity complicates the development of precise and effective therapies that can specifically modulate ferroptosis without disrupting other essential cellular processes