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At the moment, some medications can collaborate in the treatment of MASLD, some of them approved for the treatment of comorbidities such as GLP-1 agonists indicated for the treatment of T2DM or obesity, but also with benefit in the MASH treatment ( 3 The mechanisms of GLP-1 with dual or triple receptor agonists in MASLD treatment 3.1 The mechanisms of GLP-1 receptor agonists in MASLD treatment 3.1.1 Regulation of hepatic lipid metabolism GLP-1RAs exert multifaceted regulatory effects on hepatic lipid metabolism, which are pivotal to their therapeutic potential in MASLD
For there to be cost-effectiveness in saving money on claims related to cardiovascular disease, these drugs for weight loss should be priced at $7,500 to $9,800 annually
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Triple agonists may target GLP-1, GIP and glucagon receptors [12]
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