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Extremes matter: patients under 50 kg often do well at the lower end, patients over 100 kg may sit at the upper end of standard ranges
The 10mg format is suited to multi-arm or longer-duration preclinical protocols
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Similarly, SMARCB1 (a subunit of cBAF and PBAF) ChIP-seq signals in SMARCB1-rescued cells (+ SMARCB1) derived from SMARCB1-deficient TTC1240 cell lines localized to regions proximal and distal from the TSS of the SLC7A11 locus (Fig
In animal studies it is administered once daily subcutaneously, intraperitoneally or orally (gastric-stable)
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