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The supporters of coffee enemas often tout the antioxidant or anticancer properties of coffee enemas by claiming the cafestol palmitate in coffee promotes glutathione S-transferase, which detoxifies the products of tumour cell metabolism, and that the enema fluid stimulates movement of the colon and drainage of toxic substance from the gut

Genetics, blood pressure, cholesterol, diabetes, smoking, kidney function, age, and lifestyle remain major determinants of cardiovascular risk

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Current Chemical Biology, 8(1), 1522