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O-acetyl-l-carnitine (Ac-Carn) supplementation was used as a positive control (n = 4 technical replicates representative from 2 independent experiments)
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The combined diagnostic model of EV-CAT1 and carcinoembryonic antigen had ideal detection efficiency (sensitivity 66.7%, specificity 92.0%, AUC value 0.907
The Vermeulen study found a clear divergence in therapeutic effects: Acetyl-L-Carnitine (ALCAR) had a statistically significant, targeted positive effect on mental fatigue and cognitive concentration , whereas Propionyl-L-Carnitine was more effective for general, physical fatigue
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